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2016; 8(1): 19-23

Published online August 31, 2016

Copyright © Korean Society for Pharmacoepidemiology and Risk Management.

Understanding and Management of Hypersensitivity Reactions to Iodinated Contrast Media

요오드화 조영제 과민반응에 대한 이해와 임상적 대처

Dong Yoon Kang,MD1,2, Kyung Hee Sohn,MD3, Sung Yoon Kang,MD3, Soon Ho Yoon,MD4, Young Hun Choi,MD4 and Hye-Ryun Kang, MD, PhD1,2,3

강동윤1,2, 손경희3, 강성윤3, 윤순호4, 최영훈4, 강혜련1,2,3

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

With the development and introduction of advanced medical imaging technology using iodinated contrast media (ICM), ICM related adverse events are rapidly increasing. Both immediate and delayed type hypersensitivity reactions (HSRs) can occur by ICMs. Immediate HSRs can develop as an allergic-like reaction by stimulating mast cells or a chemico-physiological reaction according to ionicity or osmolality of ICM. Immediate HSRs can be classified into mild, moderate, and severe based on the severity. HSRs are infrequent but can be fatal and result in life-threatening situation. Therefore, preparation and training for the prompt management is important. In this review, we dealt with how to manage HSRs to ICM and what to prepare for the high risk patients at the time of re-exposure in order to prevent ICM related HSRs and minimize the risk of fatality. (JPERM 2016;8:-23): Contrast media; Hypersensitivity; Premedication; Secondary prevention

Keywords Contrast media, Hypersensitivity, Premedication, Secondary prevention

Korean Society for Pharmacoepidemiology and Risk Management

Vol.16 No.2
September, 2024

eISSN 2982-5954

Frequency: Bimonthly

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