Ex) Article Title, Author, Keywords
Ex) Article Title, Author, Keywords
Journal of Pharmacoepidemiology and Risk Management 2020; 12(1): 1-7
Published online March 31, 2020
Copyright © Korean Society for Pharmacoepidemiology and Risk Management.
Young-Mi Ah, PhD1 and Ju-Yeun Lee, PhD2
아영미1, 이주연2
Correspondence to:Ju-Yeun Lee, PhD
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea
Tel: +82-2-3668-7472, Fax: +82-2-874-4169
E-mail: jypharm@snu.ac.kr
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Older adults are at risk of adverse events associated with the use of potentially inappropriate medications (PIMs). PIMs
may be defined as medications where the risk of adverse health outcomes associated with its use likely outweighs its
clinical benefits when safer and more effective alternatives are available, therefore its use among older adults should be
avoided. In this review, we presented the multiple implicit and explicit prescribing tools that have been developed inter
nationally to identify potentially inappropriate prescribing and to improve prescribing in older adults. Implicit criteria, which
are not drug or disease specific and depend on the clinical expertise, are quality indicators of prescribing. The Medica
tion Appropriateness Index, Prescribing Optimization Method, Preventing Hospital Admissions by Reviewing Medication
developed by Netherlands are the examples of implicit criteria. Since the first explicit prescribing tool, the Beers’ cri
teria, developed in the United States in 1991, many explicit criteria for specific countries such as McLeod criteria,
French criteria, NORGEP criteria, PRISCUS, Australian Prescribing Indicators Tool, the Screening Tool of Older People’s
potentially inappropriate Prescriptions (STOPP) and Screening Tool to Alert physicians to the Right Treatment (START)
criteria, and EURO-FORTA (Fit fOR The Aged) has been developed and updated through systematic literature review
and expertise consensus. Consensus list of PIMs for Korean older adults was also developed. The prevalent classes of
PIM were long acting benzodiazepines, hypnotics, typical antipsychotics, long-term use of traditional nonsteroidal anti-in
flammatory drugs, tricyclic antidepressants, and anticholinergics such as first generation antihistamines and antispasmodics.
Negative clinical outcomes associated with the use of PIMs were also reviewed. (JPERM 2020;12:1-7)
: Potentially inappropriate medication list; Aged; Inappropriate prescribing
Keywords Potentially inappropriate medication list, Aged, Inappropriate prescribing ,
