Ex) Article Title, Author, Keywords
Ex) Article Title, Author, Keywords
2018; 10(2): 87-90
Published online September 30, 2018
Copyright © Korean Society for Pharmacoepidemiology and Risk Management.
Sujeong Kim, MD,Han-Ki Park,MD and Jong-Myung Lee, MD, PhD
김수정, 박한기, 이종명
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Macrolides have been considered as safe antibiotics that rarely cause hypersensitivity reactions. However, as macrolides have been widely prescribed for various diseases due to its antimicrobial and immunomodulatory properties, reports of hypersensitivity reactions caused by these drugs have also increased. Although cross-reactions among macrolide antibiotics are known to be uncommon, studies about macrolides cross-reactivity are scarce so far. We have recently experienced a rare case of Stevens-Johnson syndrome (SJS) probably induced by roxithromycin. The patient repeated the same adverse reactions after taking clarithromycin. Clinicians should consider macrolides as one of the culprit drugs of severe cutaneous adverse reaction such as SJS, and be aware of the potential for cross-reaction between macrolides. (JPERM 2018;10:-90)
: Stevens-Johnson syndrome; Macrolides; Roxithromycin; Clarithromycin; Cross reactions; Drug hypersensitivity
Keywords Stevens-Johnson syndrome, Macrolides, Roxithromycin, Clarithromycin, Cross reactions, Drug hypersensitivity
